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Micro/NanoCapsule Affinity Sensors
These capsules represent one embodiment of our sensors intended for dermal implantation. We have developed prototype sensors using glucose as a model analyte, where a protein receptor with high selectivity for glucose is used. By attaching molecular tags to our binding protein and/or a competing ligand (e.g. dextran), we can optically monitor the amount of glucose present in a sample. Our sensors employ specialized nanofilms to encapsulate the sensing reagents, enabling continuous, reversible response to glucose changes over a desired range (see response).
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