Biomedical Engineering, Texas A&M
Dwight Look College of Engineering, Texas A&M University
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Graduate Courses

601 Foundations of Biomedical Engineering Analyses
(3-0). Credit 3. Analysis of biomedical engineering processes involving interactions between biological tissues and electromagnetic waves using methodologies from developed physical principles; applications include electric and magnetic fields in biological tissues, and electromagnetic wave treatment of fundamental light propagation properties in biological tissues such as transmission, reflection, polarization, interference and diffraction.
Prerequisite: MATH 308.

602 Instrumentation and Measurement of Biomedical Systems
(3-3). Credit 4. Information measurement from biomedical systems; interface matching; transducers commonly used in biomedical engineering as the interface between biomedical signals and instrumentation systems.
Prerequisites: BMEN 309 and 401 or equivalent.

603 Information Processing in Biomedical Engineering
(3-3) Credit 4. Methods for evaluating alternative approaches in signal processing systems for biomedical applications; provides familiarity with the variety of existing software and hardware systems.
Prerequisite: BMEN 309.

605 Virtual Instrumentation Design for Medical Systems
(2-3) Credit 3. Design of medical systems using graphics programming language of LabVIEW including the designing and programming of three virtual systems: cardiac monitor, electromyogram system for biomechanics, and sleep stage analyses for electroencephalograms.
Prerequisite: Graduate classification.

607 Clinical Engineering
(3-0) Credit 3. Responsibilities, functions and duties of the hospital based biomedical engineer, including program organization, management, medical equipment acquisition and use, preventive maintenance and repair and hospital safety.
Prerequisite: Approval of instructor.

608 Optical Diagnostic and Monitoring Principles
(3-0) Credit 3. Engineering design principles of optically based monitoring and diagnostic modalities; emphasis on generating quantitative descriptions of biochemical and biophysical interactions of optic and fiber optic systems as applied to medical diagnostics and sensing.
Prerequisites: MATH 308; PHYS 208.

609 Optical Therapeutic and Interventional Principles
(3-0) Credit 3. Study of optical and thermal processes of laser interaction with biological tissue; issues and objectives in therapeutic, surgical, and diagnostic applications; basic engineering principles used in developing therapeutic with a focus on the use of lasers and optical technology.
Prerequisite: MATH 308; PHYS 208.

610 Medical Ultrasonics
(3-0) Credit 3. Physical principles of diagnostic and therapeutic ultrasound; clinical equipment; diagnostic and therapeutic protocol; biological effects of ultrasound.
Prerequisites: PHYS 219 or equivalent, 3 hours in human physiology.

611 Biomedical Imaging Systems
(3-0) Credit 3. The physics behind the major medical imaging systems including CT, MRT, Ultrasound, and X-ray will be introduced and described; a linear systems approach will be used along with basic diffraction theory.
Prerequisite: BMEN 309; MATH 308.

612 Experimentation
(2-3) Credit 3. General concepts forming the basis of the scientific method and design of experiments; analytical instrumentation and measurement methods useful in biomedical research; criteria for the selection, care, and use of experimental animals and human subjects in biomedical research.
Prerequisite: 3 hours in physiology.

614 Modeling of Biomedical Systems
(3-0) Credit 3. Principles, objectives and approaches to describing physiological phenomena with mathematical models with emphasis on mammalian systems.
Prerequisites: 3 hours in physiology, 3 hours in differential equations.

619 Engineering Analyses of Artificial Internal Organs
(3-0) Credit 3. Design, development and evaluation of artificial internal organs.
Prerequisites: BMEN 452; VTPP 335 or equivalent.

620 Bio-Optical Imaging
(3-0) Credit 3. Optical imaging techniques for detection of structures and functions of biological tissues; basic physics and engineering of each imaging technique.
Prerequisites: BMEN 601; MATH 308.

621 Microscale Bio-Optical Applications
(3-0) Credit 3.  Introduction to the biomedical application of lasers to manipulation, detection, and visualization on (sub)cellular length scales, with emphasis on governing principles on which applications are founded; applications from recent literature (state-of-the-art) presented.
Prerequisites: Graduate classification and approval of instructor

624 Biomedical Sensing and Imaging at the Nanoscale
(3-0) Credit 3.  This course serves as an introduction to nanotechnology with an emphasis on biomedical techniques and medical applications. The material covered ranges from the basic physics of contrast agents to the engineering of current sensing and imaging systems applied at the nanoscale.
Prerequisites: Graduate classification, PHYS 208, MATH 308.

630 Global Medical Device Regulation
(3-0) Credit 3. Overview of applicable U.S. and international regulations and regulatory processes for the design, approval and marketing of medical devices.
Prerequisites: BMEN 310 and graduate classification.

631 Thermodynamics of Biomolecular Systems
(3-0) Credit 3. Introduces equilibrium and non-equilibrium statistical mechanics and applies them to understand various bimolecular systems; including ensemble theroy, reaction kinetics, nonlinear dynamics, and stochastic processes; with applied examples such as enzyme-ligand binding kinetics, conformational dynamic of proteins and nucleic acids, population dynamics, and noise in biolocigal signals.
Prerequisites: Graduate classification, BMEN 240, PHYS 208, MATH 308.

632 Molecular and Cellular Biomechanics
(3-0) Credit 3. Introduces Biomolecules and their assemblies that play structural and dymanical roles in subcellular to cellular level mechanics, with emphasis on quantitative/theoretical descriptions, and discussions of the relevant experiment approaches to probe these nano to micro-scale phemomena; including topics in (1) self-assembly of cytoskeleton and biomembranes, (2) molecular motors, (3) cell motility, and mechanotransduction.
Prerequisites: Graduate classification, BMEN 240, MATH 308.

635 Biomaterials Compatibility
(3-0). Credit 3. Relevance of mechanical and physical properties to implant selection and design; effect of the body environment on metallic, ceramic, and plastic materials; tissue engineering; rejection mechanisms used by the body to maintain homeostasis regulatory requirements.
Prerequisite: Approval of instructor.

638 Control Mechanisms in Living Systems
(3-0) Credit 3. Application of control theory to the dynamic characteristics of electro-physiological and biochemical processes and to the natural and artificial maintenance of homeostasis in living systems.
Prerequisites: BMEN 401; MATH 308; 3 hours of physiology.

640 Design of Medical Devices
(3-0) Credit 3. Overview of the multiple issues in managing the design of a marketable medical device, including the design process from clinical problem definition through prototype and clinical testing to market readiness; includes FDA pre-and post-market regulation, human factors and system safety considerations, and medical product liability.
Prerequisite: Graduate classification in engineering.

650 Biomedical Optics Laboratory
(2-3) Credit 3. Biomedical optics technology; basic engineering principles used in developing therapeutic and diagnostic devices; a series of hands-on labs will be performed including optical monitoring, diagnostic and therapeutic experiments.
Prerequisites: MATH 308; PHYS 208.

660 Vascular Mechanics
(3-0) Credit 3. Application of continuum mechanics to the study of the heart arteries; on the measurement and quantification of material properties, and the calculation of vascular stresses; analysis of several cardiovascular devices to reinforce the need for careful analysis in the device design.
Prerequisites: BMEN 302 and 421 or equivalent; graduate classification.

661 Cardiac Mechanics
(3-0) Credit 3. Application of continuum mechanics and computational solid mechanics to the study of the mammalian heart; utilization of continuum mechanics and finite element analysis in solving nonlinear boundary value problems in biomechanics.

662 Vascular Fluid Mechanics
(3-0) Credit 3.  Bio-fluid mechanics of the human circulatory system including examination of disease development and medical treatments.
Prerequisites: Graduate classification and BMEN 240 or equivalent.

663 Soft Tissue Mechanics and Finite Element Methods
(3-0) Credit 3.  Application of continuum mechanics and finite elements methods to the study of the mechanical behavior of soft tissues and associative applications in biomedicine.
Prerequisites: Graduate classification and BMEN 240 or equivalent.

668 Biothermomechanics
(3-0) Credit 3. Application on continuum thermomechanics to quantify soft tissue behavior in response to combined thermal and mechanical loads including thermoelasticity and thermal damage.
Prerequisites: BMEN 240, 341, and graduate classification.

669 Entrepreneurial Issues in Biomedical Engineering
(3-0) Credit 3.  Description and analysis of issues associated with initiating business ventures to transfer biomedical technologies into the health care sector, including intellectual property protection, seed funding alternatives, and business strategies relevant to the biomedical engineering technology area; and utilizing recent case studies of previous ventures.
Prerequisites: Graduate classification.

671 Introduction to Modeling of Biological Systems with Mathematics
(3-0) Credit 3. Construction and solution of mathematical and simulation models using mathematical programming, numerical methods packages, concepts of parallel and rule-based programming, incorporating pattern matching techniques, visualization of results with graphical packages; examples from various fields of study such a fractal geometry, cellular automata, chaoe, matrix population models and ecosystems modeling.
Prerequisites: BMEN 601 or equivalent; one computer course.

673 Radiation Biology
(3-0) Credit 3. The response of biological systems to ionizing radiation at the molecular, cellular, and organismal levels; effects of different dose levels with emphasis on the underlying mechanisms relevant to long-term health effects at low doses.
Prerequisite: NUEN 409 or graduate classification. Cross-listed with NUEN 673.

674 Communications in Biomedical Engineering
(2-0) Credit 2.  General concepts for communicating the results of biomedical research including written papers, conference proceedings, proposals and grants, as well as oral presentations and basic ethics.
Prerequisite:  Graduate classification or approval of instructor.

675 Biomedical Case Studies
(1-0) Credit 1.  Introduction to the engineering design process for solving biomedical problems by using the case study method in biomedical instrument design.
rerequisite: Graduate classification or approval or instructor.

680 Biomedical Engineering of Tissues
(3-0) Credit 3.  Introduction to aspects of tissue engineering with an emphasis placed on tissue level topics including tissue organization and biological processes, with insights from recent literature (state-of-the-art).
Prerequisites: Graduate classification or approval of instructor.

681 Seminar
(1-0) Credit 1. Designed to permit student to broaden capability, performance and perspective in biomedical engineering via his or her own formal presentation and by presentations by other professionals.

684 Professional Internship
Credit 1 or more each semester. Training under the supervision of practicing engineers in settings appropriate to the student's professional objectives.
Prerequisites: Approval of chair of student's advisory committee and chair of biomedical engineering department.

685 Directed Studies
Credit 1 to 12 each semester. Allow students the opportunity to undertake and complete for credit limited investigations not included within thesis or dissertation research and not covered by other courses.
Prerequisite: Approval of department head.

689 Special Topics in . . .
Credit 1 to 4. Selected topics in an identified area of biomedical engineering. May be repeated for credit.
Prerequisite: Approval of instructor.

691 Research
Credit 1 or more each semester. Research for thesis or dissertation.